ABSTRACT
Angiokeratoma corporis diffusum [ACD] is a rare clinical type of angiokeratoma and has been reported, mostly, in association with various life threatening conditions, of which Fabry disease is the most known. Rarely, it has been reported as an isolated finding without any systemic features. A 23-year-old male presented with numerous red papules of various sizes with a history of intermittent bleeding. Histopathology findings were consistent with angiokeratoma and our case was diagnosed as ACD. We herein present a case of cutaneous variant of ACD without any associated systemic associations. Also, the conditions associated with ACD have been briefly discussed.
Subject(s)
Humans , Male , Skin/pathology , Angiokeratoma , Dilatation, Pathologic , Aspartylglucosaminuria , FucosidosisABSTRACT
Alopecia areata [AA] is a chronic inflammatory condition that affects the hair follicles and sometimes, the nails. It is believed that AA is caused by T cell-mediated autoimmune response and increased frequency of other autoimmune diseases in persons suffering from AA supports this hypothesis. A 12-year-old boy presented with extensive alopecia areata with pitting in all nails for 6 years. He had developed lesions of vitiligo and lichen planus on trunk in a segmental manner. While the association of alopecia areata and vitiligo as well as lichen planus is well known, segmental nature of both vitiligo and lichen planus is quite rare
Subject(s)
Humans , Male , Vitiligo/diagnosis , Lichen Planus/diagnosis , NailsABSTRACT
A 17-year-old girl presented with multiple perifollicular hemorrhagic lesions on legs for 2 weeks. There was history of intermittent gum bleeding for last 2 months. Clinical examination revealed follicular keratosis and broken twisted hair [corkscrew hair], in addition to hemorrhagic lesions. Perifollicular hemorrhagic lesions and corkscrew hair are virtually pathognomonic for scurvy. When specifically asked, mother revealed that the girl was on self-imposed diet with almost no citrus fruits. Based on history and clinical findings, diagnosis of scurvy was made. The response to vitamin C supplementation was very good and all the lesions disappeared within one month. Scurvy has been reported in increasing numbers in recent literature; hence, recognition of scurvy is essential to avoid many serious complications including internal bleeding and even, death
Subject(s)
Humans , Female , Scurvy/diagnosis , Ascorbic Acid Deficiency/complications , Hair , Hemorrhage , Leg , KeratosisABSTRACT
Inverse [flexural] psoriasis is characterized by shiny, pink to red, sharply-demarcated thin plaques. Frequency of isolated involvement of these areas is very rare and the morphology is frequently altered by maceration and friction. All this leads to diagnostic confusion. We describe two cases of inverse psoriasis with isolated involvement of axillae. One patient presented with dry mildly scaly plaque, while the other presented with macerated plaque. Histopathology was consistent with the diagnosis of inverse psoriasis. Although there are previous reports, but localization of lesions only to axillae in a case of inverse psoriasis is unique